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Channel: Publications at the New York Academy of Sciences - Chemistry & Chemical Engineering
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Src Kinase Inhibitors as Anticancer Agents

Kim Arndt, director in oncology at Wyeth Research, discusses compounds his company analyzed for their ability to inhibit tumor growth in mice.

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Chemical Biology

How the tools of an emerging interdisciplinary field are helping scientists to explain cell activity and develop new drugs.

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Better Living through Chemistry

Novel small molecules, temporally activated proteins, and highly engineered peptides are offering new methods for understanding cell biology.

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Greening the Built Environment

New materials like glass concrete and electrochromic windows can save energy and valuable resources.

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The Shape of Things

Scientists are creating nonnatural receptors, nucleic acid analogs, and small molecules to bypass natural defense mechanisms that hinder treatment of diseases or infections.

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Cells and Sulfur

Research in sulfur biochemistry will increase our ability to fight pathogens, produce vitamins, and understand basic metabolism.

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Science In Silico

At one time scientists' most valuable tools were microscopes and telescopes. Today, in fields as diverse as systems biology, protein modeling, and weather prediction, it may well be the computer.

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Structural Creativity

Non-natural β-peptides, peptide nucleic acids, and peptoids can serve as probes, scaffolds, and building blocks for protein-like structures.

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Green Chemistry

A growing awareness of the disadvantages of current industrial practices has resulted in the development of safe and efficient technologies that use renewable resources.

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Designer Generation

Computational design and other techniques illustrate the variety of ways to use chemistry to solve biological problems.

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How to Build a Better Protein

Natural protein design has been refined over billions of years of evolution, but scientists are now taking on this task using principles gleaned from mere decades of study.

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Incredible Anaerobes: From Physiology to Genomics to Fuels

The volume presents current work on the physiology and unique features of anaerobes.Full table of contents

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The Maillard Reaction: Recent Advances in Food and Biomedical Sciences

This volume addresses a wide range of interdisciplinary research reports on the role of Maillard reactions in aging and disease.Full table of contents

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Biocatalysts and Biosurfactants

Microbial products can take the place of toxic chemicals in some chemical syntheses, reducing undesirable impacts on the environment and human health.

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Turn Down the Volume

Mini-laboratories for studying protein crystallization and viscous polymer behavior reveal the power and beauty of small scale approaches.

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Steroid Enzymes and Cancer

An exploration of the consequences of abnormal synthesis of steroid hormones in individual target tissues, a process that has assumed an increasing importance in our understanding of malignancies.

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Charge and Release

Researchers are developing "intelligent" materials that respond to changes in their environment in ways that solve engineering challenges. Products like "smart" food packaging have even begun entering...

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Potent Pathways

Protein kinases play a key role in almost every major pathway in eukaryotic cells. Structural approaches, including a new method called fragment-based drug design, are identifying potential targets...

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Trends in Chemical Biology 2009

Graduate students and postdocs from chemical biology labs around the New York area describe efforts to find and synthesize molecules that bind to proteins or DNA in useful ways.

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Something Borrowed, Something New

From traditional Asian herbs to high-tech computational approaches, chemical biologists are using everything in their arsenal to identify promising new drug candidates.

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